0249 Effects of Alcohol Consumption on Sleep-Wake Pattern of a Rat Model of Anxiety
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Abstracto
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Introduction
Anxiety is an important factor for self-administered alcohol as a tool to reduce its symptoms. However, alcohol is capable to disrupt sleep-wake patterns in subjects with medium- to high-alcohol consumption. We have selectively bred two sublines from Sprague-Dawley rats that differ on its yawning frequency. High-yawning (HY) rats have a mean of 20 yawns/h, whereas the Low-yawning (LY) rats have only 2 yawns/hour. LY rats also showed anxious responses when evaluated on standardized tests. The aim of this study was to assess the changes on sleep-wake patterns after chronic alcohol consumption.
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fecha de publicación
- mayo 2020
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Número de páginas
- 1 Página
Página inicial
- Pág. A95
Volumen
- Vol. 43